Possible New Risk Factor for Alzheimer's Disease

Alzheimer's Association
Monday, 4 May 1998

Researchers in England discovered a chemical imbalance in people with Alzheimer's that could provide further insight into how the disease works, and possibly how to treat it. In a study of 76 people with the disease and 108 without Alzheimer's, the scientists found an association between elevated blood levels of an amino acid called homocysteine and increased risk for Alzheimer's disease. The research was announced at an international scientific meeting in the Netherlands.

Researchers note that elevated homocysteine levels could be a result, rather than a cause, of the disease. Despite some news reports, there is no information about whether lowering homocysteine levels will have a protective effect against Alzheimer's.

Raised levels of homocysteine are a known risk factor for heart disease and stroke. Homocysteine levels are known to be affected by diet. Folic acid and B12 supplements are given to reduce homocysteine levels. People should not take folic acid supplements without consulting their doctors. There is no evidence that taking B vitamins or folic acid will lower the risk of Alzheimer's.

The Alzheimer's Association is the largest national voluntary health organization dedicated to research for the causes, treatments, prevention and cure of Alzheimer's disease and to providing education and support services to the four million Americans with the disease, their families and caregivers. You can reach the Alzheimer's Association at (800) 272-3900.

For more information, or to contact Alzheimer's Association, see their website at: www.alz.org